Yes! Duet FireWire, Duet 2 and Duet for iPad/Mac are all fully compatible with Mac OS X Yosemite (10.10 to 10.10.5). Please be sure to download and install the latest Yosemite compatible software package for your product from Apogee’s site.
Click to find the latest Duet FireWire Software Installer
Click to find the latest Duet 2 Software Installer
Click to find the latest Duet for iPad/Mac Software Installer