Does ONE work with Reason, Cubase, Ableton, or ProTools? Chris April 24, 2021 01:15 Updated Yes! ONE works with Reason, Cubase, Ableton, ProTools (version 9 and up) and any other Core Audio Compatible application on the Mac. Related articles Can I use ONE with my iPad? Can I install the ONE for iPad/Mac firmware to my original ONE (first generation) for iPad compatibility? How do I use Symphony I/O connected to ProTools HD for audio output of other apps? How do I connect ONE to powered studio monitors? Comments 0 comments Article is closed for comments.