Due to changes in macOS, the Apogee GiO is not fully compatible with macOS 10.15 Catalina or higher.
However, the USB Audio portion of the device DOES WORK because it is "class-compliant" and uses an Apple CoreAudio driver that is built into macOS.
Audio input and output
Does Not Work
All control surface and MIDI functions
Buttons or switches
For full functionality of all GiO's features, please remain on macOS 10.14 Mojave or earlier.